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SFB 685 wurde erfolgreich begutachtet und wird für weitere 4 Jahre gefördert.

Mit den folgenden Projekten geht SFB 685 in die zweite Förderperiode bis 2013. Mehr Informationen dazu bald...

 

Project (code)

Title

Research area

Principal investigator(s)

Project Group A: Innate immunity and accessory cells

A1

Activating NK receptors and their ligands encoded in the Natural Killer Gene Complex

Immunology, cytotoxic lymphocytes

A. Steinle

 

A2

Influence of soluble factors released by dying cells on phagocytic cells of the innate immune system

Elimination of dying cells, inflammation

S. Wesselborg

K. Lauber

A3

The complex repertoires of staphylococcal Pathogen-Associated Molecular Patterns (PAMPs) and their immunomodulatory activities

Infection biology, immunology

A. Peschel

S. Autenrieth

A6

Role of mast cells in effective immune responses against tumors

Immunology, dermatology

T. Biedermann

A7

Modulation of NK cell-mediated tumor immunosurveillance by platelets

NK cell immunosurveillance, platelet biology

H. Salih

H.-G. Kopp

A8

Evasion of the NK cell-mediated immunosurveillance by the human cytomegalovirus

 

Immunology, virology

C. Sinzger

A. Steinle

A9

The impact of Wnt receptors and other stem cell differentiation molecules as novel targets for an immune-therapeutic strategy for inflammatory bowel diseases

 

Stem cell differentiation, innate immunity

J. Wehkamp

M. Schwab

 

Project Group B: T cells and the generation of antigen

B1

Systems biology of immunogenicity and immune escape

Sytems biology, bioinformatics

O. Kohlbacher

J. Bauer

B2

Proteases in the MHC class II pathway

Biochemistry, neuroimmunology

H. Kalbacher

A. Melms

B3

Structural and functional analysis of viral proteins in complex with cellular receptors

Structural biology, biochemistry

T. Stehle

B6

Non-invasive imaging of T-cell trafficking into solid tumors

Molecular imaging, tumor immunology

B. Pichler

M. Kneilling

B7

Role of novel unusual inhibitor of NF-kB proteins in T-helper cell differentiation

Immunology,
cell biology

K. Schulze-Osthoff

B8

The regulation and biological function of C/EBPβ overexpression in ALK+ anaplastic large cell lymphoma

 

Hematopathology, oncology

F. Fend

L. Quintanilla-Martinez  de Fend

Project Group C: Immunotherapy

 

C1

Control of tumor dormancy and tumor angiogenesis by CD4+ T cells

Immunology, dermatology

M. Röcken

C2

Individualized MHC-II-peptide vaccination in combination with adoptive T-cell transfer after lymphodepletion in malignant melanoma

Translational immunology, dermatooncology

C. Garbe

S. Schmidt

C3

NK cell-mediated immunotherapy of minimal residual disease after haploidentical stem cell transplantation in pediatric patients with B-lineage acute lymphoblastic leukemia

Haploidentical transplantation, NK cell-mediated immunotherapy

P. Lang

R. Handgretinger

C5

T-cell epitopes for the immunotherapy of urological cancers

Tumor immunology, biochemistry

S. Stevanović

A. Stenzl

 

C6

Characterization of the T-cell response to adenovirus and cytomegalovirus for the control of infections through adoptive T-cell transfer

Hematology, virology

T. Feuchtinger

G. Jahn

 

C9

Individual chemo-immunotherapy of peritoneal carcinomatosis

Tumor immunotherapy, genome sequencing

A. Königsrainer

S. Löb

H.-G. Rammensee

C10

Development of therapeutic antibodies for the elimination of tumor stem cells

Immunology, oncology

L. Große-Hovest

H.-J. Bühring

G. Jung

Project Group Z: Central Projects, Service Units and Integrated Graduate School

Z3

Administrative office

-

H.-G. Rammensee

Z4

Integrated Research Training Group

-

B. Schittek

A. Steinle

 

 

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